Valvular & structural heart disease
Redo-TAVI with the SAPIEN 3 valve in degenerated calcified CoreValve/Evolut explants
Authors' conclusion
S3 implantation at node 5 in calcified CV/EV valves resulted in satisfactory hydrodynamic performance in most configurations tested with stable leaflet overhang throughout the cardiac cycle.
Study context
- Population
- Explanted degenerated calcified CoreValve/Evolut transcatheter aortic valves (TAVs) with SAPIEN 3 implanted at node 5 (redo-TAVI)S3 TAVs in CV/EV explants
- Participants
- 4 participants
- Outcome
- S3 hydrodynamic performance (ISO 5840-3) in calcified CV/EV explants
Methodological detailsex vivo hydrodynamic testing, ISO 5840-3 standard
- Ex vivo hydrodynamic testing
- ISO 5840-3 standard
Main finding
As reported in the abstract
- All S3 implants showed adequate effective orifice area (EOA)
- 4
- Regurgitant fraction (RF) within accepted value (<20%)
- 3 out of 4
- CV/EV leaflet overhang
- 25-37%
- Calcified leaflets stationary through cardiac cycle
- difference <9%
- Leaflet pinwheeling from S3 frame underexpansion
- 13-30%
Original publication
Redo-TAVI with the SAPIEN 3 valve in degenerated calcified CoreValve/Evolut explants. EuroIntervention. Published 18 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →