Reversible ischaemia and outcome after adjustment for coronary artery disease severity: a multicentre stress-echocardiography registry
Authors' conclusion
Our study suggests that reversible ischaemia by wall motion assessment and CFVR-LAD on dipyridamole SE are independently associated with dismal outcome in patients with suspected or known stable CAD, even after accounting for angiographic anatomic CAD severity and also independently from which coronary artery is diseased.
Study context
- Population
- Patients with suspected or known stable coronary artery disease (CAD) who underwent high-dose dipyridamole SE (with CFVR-LAD) and coronary angiography within 2 monthsmean age 66 ± 12 years
- Participants
- 3,191 patients
- Outcome
- All-cause mortality and non-fatal MI
- Follow-up
- Median 42 months
Methodological detailsmulticentre, registry
- Multicentre
- Registry
Main finding
As reported in the abstract
Primary end point occurred
767
24%
Deaths
409
Non-fatal myocardial infarction (MI)
375
Observational data: associations, not effects.
Further findings
- Reversible ischaemia associated with subsequent MI; CFVR-LAD associated with mortality, independent of anatomic CAD severity
Original publication
Reversible ischaemia and outcome after adjustment for coronary artery disease severity: a multicentre stress-echocardiography registry. Eur Heart J Cardiovasc Imaging. Published 10 November 2023. doi:10.
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