Valvular & structural heart disease

Rheumatic Heart Disease Burden: A Comparative Analysis between the United States and the European Union

JACC AdvPublished Cross-sectional study

Authors' conclusion

The varied trends underscore the complexity of RHD epidemiology

Study context

Population
Rheumatic heart disease burden in the United States of America (USA) and the European Union (EU), 1993–2021
Exposure
USA vs EU
Outcome
RHD age-standardized prevalence (ASPR) and incidence (ASIR)
Follow-up
2021
Methodological detailsGlobal Burden of Disease Study 2021 data, Age-standardized rates and estimated annual percentage change (EAPC) from the Global Health Data Exchange query tool
  • Global Burden of Disease Study 2021 data
  • Age-standardized rates and EAPC from the Global Health Data Exchange query tool

Main finding

As reported in the abstract

GroupASPR 2021ASPR annual trend since 1993ASIR 1993 to 2021ASPR annual trend 1993–2021
USA123.4/100,000decreasing 0.32%10.6 to 10.0/100,000
EU49.7/100,0007.43 to 4.6/100,000decreasing 1.6%

ASPR 2021

USA123.4/100,000
EU49.7/100,000

ASPR annual trend since 1993

USAdecreasing 0.32%
EU— not stated in the abstract

ASIR 1993 to 2021

USA10.6 to 10.0/100,000
EU7.43 to 4.6/100,000

ASPR annual trend 1993–2021

USA— not stated in the abstract
EUdecreasing 1.6%

Observational data: associations, not effects.

Further findings

Drivers of US prevalence and incidence change

Primarily driven by Florida, Nevada and Tennessee
Reversal in rheumatic heart disease (RHD) burden in the USA since 2007

Sex disparity

Significant gender disparity with female predominance in both regions

Age-standardized DALYs and YLLs

Higher in the EU than the USA

Original publication

Rheumatic Heart Disease Burden: A Comparative Analysis between the United States and the European Union. JACC Adv. Published 11 November 2024. doi:10.1016/j.jacadv.2024.101393

Composed by AI from the published abstract and checked against it. How Briefs are made →

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