Risk factor associations with individual myocardial infarction subtypes and acute non-ischemic myocardial injury in the Multi-Ethnic Study of Atherosclerosis (MESA): Design and rationale
Study context
- Population
- MESA, a large prospective primary prevention cardiovascular study; events over the first 14 years of follow-up4,080 events re-adjudicated
- Primary endpoint
- Incidence and risk factor profile of individual myocardial injury subtypes (MI type 1 to 5, acute non-ischemic myocardial injury, chronic myocardial injury)
- Follow-up
- First 14 years
Methodological details2-physician adjudication, Fourth Universal Definition of myocardial infarction (MI), Re-adjudication of events by 2 physicians using medical records, abstracted data collection forms, cardiac biomarker results and ECGs, Associations of baseline traditional and novel CV risk factors with incident and recurrent acute MI subtypes and acute non-ischemic myocardial injury to be compared
- 2-physician adjudication
- Fourth Universal Definition of MI
- Re-adjudication of events by 2 physicians using medical records, abstracted data collection forms, cardiac biomarker results and ECGs
- Associations of baseline traditional and novel CV risk factors with incident and recurrent acute MI subtypes and acute non-ischemic myocardial injury to be compared
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Risk factor associations with individual myocardial infarction subtypes and acute non-ischemic myocardial injury in the Multi-Ethnic Study of Atherosclerosis (MESA): Design and rationale. Am Heart J. Published 2 March 2023. doi:10.
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