Risk Factors for Death or Transplant After Stage 2 Palliation for Single Ventricle Heart Disease
Authors' conclusion
Mortality and transplantation referral rates after S2P to 1 year of age remain high ∼7%. Many of the identified risk factors after S2P are similar to those established for interstage factors around the S1P, whereas others may be unique to the period after S2P.
Study context
- Population
- Infants with single ventricle heart disease undergoing staged palliation (2016–2022) who survived to stage 2 procedure (S2P)survived to S2P
- Participants
- 1,455 infants
- Outcome
- Mortality or transplantation referral after S2P
- Follow-up
- To first birthday
Methodological detailsmulticentre registry (NPC-QIC), Multivariable logistic regression and classification and regression trees
- Multicentre registry (NPC-QIC)
- Multivariable logistic regression and classification and regression trees
Main finding
As reported in the abstract
Death or transplant referral after S2P
Died
5.2%
Referred for transplant
2.3%
Overall event rate at 30 days after S2P
2%
Overall event rate at 100 days after S2P
5%
Observational data: associations, not effects.
Original publication
Risk Factors for Death or Transplant After Stage 2 Palliation for Single Ventricle Heart Disease. JACC Adv. Published 10 April 2024. doi:10.
Summarised from the published abstract; every number is checked against it