Risk of Death Associated with Incident Heart Failure in Patients with Known or Suspected Chronic Coronary Syndrome
Authors' conclusion
In patients with CCS, long-term rates of incident HF were higher than MI and stroke. Patients with new-onset HF showed a higher risk of long-term mortality.
Study context
- Population
- Heart failure (HF)-free patients with known or suspected chronic coronary syndrome (CCS) undergoing vasodilator stress cardiac magnetic resonance (CMR)
- Participants
- 5,811 consecutive HF-free patients
- Exposure
- Incident HF vs myocardial infarction (MI) vs stroke
- Outcome
- Incidence of HF and long-term mortality risk after HF compared with MI and stroke
Methodological detailsconsecutive patients, Markov illness-death model
- Consecutive patients
- Markov illness-death model
Main finding
As reported in the abstract
median follow-up 5.44 (IQR = 2.53-8.55) years
HF
1.02
MI
0.62
Stroke
0.51
Hazard ratio (95% CI)
HFmortality risk attributable to new-onset HF by Year 10
2.68(1.74–4.12)
HFvs MImortality, year 6.3
1.88(1.03–3.43)
- Rates of new-onset HF higher than MI and stroke
- P < 0.05
Observational data: associations, not effects.
Further findings
All-cause deaths · median follow-up 5.44 years
- Deaths registered
- 591
- Death rate per 100 P-Y
- 1.79
Original publication
Risk of Death Associated with Incident Heart Failure in Patients with Known or Suspected Chronic Coronary Syndrome. ESC Heart Fail. Published 5 October 2022. doi:10.
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