Routine Electrocardiogram Screening and Cardiovascular Disease Events in Adults
Study context
- Population
- Adults aged 35 to 65 years in the Japan Health Insurance Association annual health check program, 2015–2022
- Participants
- 3,698,429 adults
- Exposure
- Baseline electrocardiogram (ECG) abnormality vs normal ECG
- 1 minor ECG abnormalityn = 623,073
- ≥2 minor ECG abnormalitiesn = 144,535
- Major ECG abnormalityn = 56,921
- Outcome
- Composite of:
- Overall death and CVD hospital admission due to MI
- Stroke
- HF
- Follow-up
- Median 5.5 (IQR, 3.4-5.7) years
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
Each group vs normal ECGAdjusted hazard ratio (95% CI)
1 minor ECG abnormality
1.19(1.18–1.20)
≥2 minor ECG abnormalities
1.37(1.34–1.39)
Major ECG abnormality
1.96(1.92–2.02)
Observational data: associations, not effects.
Secondary outcomes
Incidence rate, per 10 000 person-years
| Outcome | Normal ECG | 1 minor ECG abnormality | ≥2 minor ECG abnormalities | Adjusted HR (95% CI) | |
|---|---|---|---|---|---|
| Developing a new major ECG abnormality1 minor ECG abnormalityvs Normal ECG | 85.1 (95% CI 84.5–85.5) | 217.2 (95% CI 215.5–219.0) | 306.4 (95% CI 302.1–310.7) | 2.52 (2.49–2.55) | |
| Developing a new major ECG abnormality≥2 minor ECG abnormalitiesvs Normal ECG | 3.61 (3.55–3.67) | ||||
| 0.20.5125Adjusted hazard ratio (log scale) |
Original publication
Routine Electrocardiogram Screening and Cardiovascular Disease Events in Adults. JAMA Intern Med. Published 1 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →