Valvular & structural heart diseaseCohort study
Self-Reported Quality of Life and 30-Day Mortality in Elective Cardiac Surgery
- retrospective cohort study
- analyzed prospectively collected data
- 2-step cluster analysis
- multivariable Cox models
Authors' conclusion
Lower preoperative HRQoL was independently associated with higher 30-day mortality following elective cardiac surgery. Increased mortality following complications in patients with lower HRQoL suggests limited physiological reserve. Incorporating HRQoL, particularly physical health, may improve preoperative risk stratification.
Study context
- Population
- Adults undergoing elective cardiac surgery at Maastricht University Medical Center (2018–2023)patients analysed
- Participants
- 2,259 adults
- Exposure
- Thirty-day mortality and composite morbidity were compared between clusters
Main finding
As reported in the abstract
died within 30 days
55 (2.43%)
Observational data: associations, not effects.
Further findings
Mortality · 30 days — higher HRQoL group vs lower HRQoL group · lower in the higher HRQoL group
P < 0.001
Composite morbidity · less often in the higher HRQoL group
P = 0.026
Mortality among patients with complications · lower in the higher HRQoL group · among patients with complications
P = 0.031
| Outcome | Estimate | P value | |
|---|---|---|---|
| Mortality · 30 days — lower HRQoL group vs higher HRQoL group · higher mortality with lower HRQoL; independently associated | adjusted HR 2.22 (95% CI 1.23–4.02) | P = 0.008 | |
| Mortality by Physical Component Summary · higher score associated with lower mortality | HR per 10-point increase 0.66 (95% CI 0.49–0.91) | P = 0.01 | |
| 0.20.5125Ratio (log scale) |
Mortality by Physical Component Summary
- Mental Component Summary not associated with mortality
Original publication
Summarised from the published abstract; every number is checked against it