Heart failure & cardiomyopathies
Severity of mobility limitation and adverse outcomes in heart failure
Authors' conclusion
This study demonstrates a strong and graded association between mobility limitation severity and adverse outcomes in HF, suggesting its utility for refined risk stratification.
Study context
- Population
- Hospitalised patients with heart failure (HF)hospitalised patients with HF from two prospective Japanese cohort studies
- Participants
- 2,103 patients
- Comparison
- Mobility limitation at discharge, categories II, III and IV vs category I
- Outcome
- Composite of:
- HF rehospitalisation
- All-cause mortality
- Follow-up
- 2 years
Methodological detailsno exclusion criteria
- No exclusion criteria
Pooled result
As reported in the abstract
Each group vs category IAdjusted hazard ratio (95% CI)
Category II
1.22(1.04–1.45)
Category III
1.39(1.11–1.73)
Category IV
1.71(1.34–2.20)
- Composite outcomes
- 998
- Person-years of follow-up
- 2820.7
Further pooled results
- Graded association clear for mortality
- Graded association less evident for HF rehospitalisation alone, likely reflecting competing mortality risks
Original publication
Severity of mobility limitation and adverse outcomes in heart failure. Heart. Published 18 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →