Sex Differences in Ventricular Arrhythmias and Adverse Outcomes Following Acute Myocardial Infarction
Main finding · Ventricular arrhythmias after acute MIResult — go to the resultAdjusted odds ratio 1.72 CI 1.67–1.78Authors' conclusion
Women had lower odds of VAs but worse hospital outcomes overall.
Study context
- Population
- Patients admitted for acute MI, US National Inpatient Sample 2016–2020174,565 with ventricular arrhythmias (VAs)
- Participants
- 1,543,140 patients
- Exposure
- Women vs men
- Outcome
- Incidence of ventricular arrhythmias after acute MI and in-hospital outcomes, by sex
- Follow-up
- In-hospital
Methodological detailsNational Inpatient Sample 2016 to 2020, multivariable logistic regression
- National Inpatient Sample 2016 to 2020
- Multivariable logistic regression
Main finding
Ventricular arrhythmias after acute MI
Adjusted odds ratio
1.72
CI 1.67–1.78
P < 0.001
By group
Menvs Women
adjusted OR 1.72 (CI 1.67–1.78); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted OR (CI) | P value | |
|---|---|---|---|
| In-hospital outcomes in patients with VAs after acute MIWomenvs MenIn-hospital mortality | 1.32 (1.21–1.42) | P < 0.001 | |
| In-hospital outcomes in patients with VAs after acute MIWomenvs MenCardiogenic shock | 1.08 (1.01–1.15) | P < 0.022 | |
| In-hospital outcomes in patients with VAs after acute MIWomenvs MenCardiac arrest | 1.11 (1.03–1.18) | P < 0.002 | |
| Procedures during index admissionWomenvs MenICD | 0.57 (0.47–0.68) | P < 0.001 | |
| Procedures during index admissionWomenvs MenCatheter ablation | 0.51 (0.27–0.98) | P < 0.001 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Original publication
Sex Differences in Ventricular Arrhythmias and Adverse Outcomes Following Acute Myocardial Infarction. JACC Adv. Published 3 July 2024. doi:10.
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