Time Trends in Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention: Meta-Analysis on Sex Differences
Authors' conclusion
In the meta-analysis of PCI-related trials in ACS, women have a higher risk of adverse cardiovascular outcomes compared with men.
Study context
- Population
- Patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI)32 trials
- Comparison
- Women compared with men
- Outcome
- major adverse cardiovascular events (MACE) and its components
- Follow-up
- Short-term (within 1 month after PCI), mid-term (within 1 year), and long-term (within >1 year)
Methodological detailsrandom effects model
- Random effects model
Pooled result
As reported in the abstract
women vs menRelative risk (95% CI)
MACE, short-term
1.43(1.10–1.86)
All-cause mortality, short-term
2.51(1.70–3.71)
Myocardial infarction, short-term
1.33(1.00–1.77)
MACE, long-term
1.11(1.01–1.22)
All-cause mortality, long-term
1.29(1.17–1.42)
Cardiovascular mortality, long-term
1.30(1.11–1.52)
Original publication
Time Trends in Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention: Meta-Analysis on Sex Differences. JACC Adv. Published 8 January 2025. doi:10.
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