Arrhythmias & electrophysiology

Shortened radiofrequency delivery time to optimize efficiency and safety of pulmonary vein isolation with the radiofrequency balloon: insights from the COLLABORATE registry

EuropacePublished Prospective multicentre registry study

Authors' conclusion

Analyses from the COLLABORATE registry demonstrate that shortening RF energy delivery times to 15/45 s (PST/ANT) during PVI with the RFB resulted in comparable freedom from recurrent atrial tachyarrhythmia compared to conventional delivery times with comparable efficiency and safety.

Study context

Population
Patients undergoing pulmonary vein isolation (PVI) with a radiofrequency balloon
Participants
641 patients
Exposure
Shortened RF delivery vs conventional RF delivery for PVI with radiofrequency balloon (RFB)
  • SHRTn = 267
  • CONVn = 374reference
Outcome
Freedom from any atrial tachyarrhythmias
Follow-up
1 year
Methodological details7 European centres
  • 7 European centres

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Procedure time

P < 0.001

Fluoroscopy time

P < 0.001

First-pass isolation rates and time to isolation

Comparable between groups

Safety

OutcomeP value
Procedural complications1.4% vs. 5.3%, lower with shortened RF deliveryP = 0.04

Original publication

Shortened radiofrequency delivery time to optimize efficiency and safety of pulmonary vein isolation with the radiofrequency balloon: insights from the COLLABORATE registry. Europace. Published 4 September 2024. doi:10.1093/europace/euae227

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