Coronary disease & ACS

Single high-sensitivity troponin levels to assess patients with potential acute coronary syndromes: 1-year outcomes

HeartPublished two cohorts

Authors' conclusion

A clinical pathway which incorporates early discharge based on a single low serum hs-cTnI is associated with an increased proportion of patients with a potential ACS discharged directly from the ED and reduced length of stay, without an increase in death or MI at 1 year.

Study context

Population
Patients with a potential acute coronary syndrome (ACS), without high-risk featuresrecruited between May 2018 and October 2019
Participants
2,255 patients
Comparison
STAT pathway vs standard pathway
  • STATn = 1,124
  • Standardn = 1,131
Outcome
Discharged directly from emergency department (ED)
Methodological details12-month outcomes assessed using linked administrative data
  • 12-month outcomes assessed using linked administrative data

Main finding

As reported in the abstract

Further findings

All-cause death (unadjusted) · 12 months · no significant difference

P = 0.35

Myocardial infarction (MI) (unadjusted) · 12 months · no significant difference

P = 0.13

Median hospital length of stay

Reduction in median hospital length of stay with STAT
47 min

Baseline characteristics

Mean age
55 years
Male
53%

Original publication

Single high-sensitivity troponin levels to assess patients with potential acute coronary syndromes: 1-year outcomes. Heart. Published 27 June 2025. doi:10.1136/heartjnl-2024-325188

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