Arrhythmias & electrophysiology
Spatially Conserved Spiral Wave Activity During Human Atrial Fibrillation
Authors' conclusion
Intermittency of spiral wave activity represents conserved spiral wave activity of long, but interrupted duration or transient spiral activity, in the majority of patients.
Study context
- Population
- Patients with AF (24 persistent AF) mapped with a 64-electrode atrial catheter24 persistent AF
- Participants
- 34 patients
- Comparison
- Clinical AF recordings vs computer simulations of spiral wave activity
- Outcome
- Whether intermittent spiral waves returned in step (conserved phase) or changed phase at the start of each interval
Methodological detailsin silico simulations, clinical mapping, 60 s recordings from a 64-electrode atrial catheter; clockwise and counterclockwise spiral waves located and angle of rotation over time computed per interval
- In silico simulations
- Clinical mapping
- 60 s recordings from a 64-electrode atrial catheter; clockwise and counterclockwise spiral waves located and angle of rotation over time computed per interval
Main finding
As reported in the abstract
Spiral waves returning in step
Patients: spiral waves returned in step
68%
P=0.05
Original publication
Spatially Conserved Spiral Wave Activity During Human Atrial Fibrillation. Circ Arrhythm Electrophysiol. Published 13 February 2024. doi:10.
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