Arrhythmias & electrophysiology
Observable Atrial and Ventricular Fibrillation Episode Durations Are Conformant With a Power Law Based on System Size and Spatial Synchronization
Authors' conclusion
Observable fibrillation episode durations are conformant with a power law based on system size and correlation length.
Study context
- Population
- Self-terminating atrial fibrillation (AF) and ventricular fibrillation (VF) episodes in computer models and human recordings
- Comparison
- Computer simulations vs VF vs AF basket vs AF grid
- VFn = 12
- AF basketn = 9
- AF gridn = 42
- Outcome
- Conformance of episode durations with a power law based on ratio of system size and correlation length
Methodological detailscomputer simulations, human ischemic VF and AF recordings
- Computer simulations
- Human ischemic VF and AF recordings
Main finding
As reported in the abstract
Power-law conformance of episode durations (R2)
- Aliev-Panfilov model R2 0.90
- P<0.001
- Courtemanche model R2 0.91
- P<0.001
- Luo-Rudy model R2 0.61
- P<0.001
- VF R2 0.86
- P<0.001
- AF basket R2 0.91
- P<0.001
- AF grid R2 0.92
- P<0.001
Further findings
Discrimination of self-terminating vs sustained AF/VF episodes, and paroxysmal vs persistent AF
- Ratio differentiated self-terminating vs sustained episodes (all systems)
- P < 0.001
- Ratio differentiated paroxysmal vs persistent AF
- P < 0.001
Other electrogram metrics (dominant frequency, Shannon Entropy, mean voltage, peak-peak voltage)
- No statistically significant differences
- P > 0.05
Original publication
Observable Atrial and Ventricular Fibrillation Episode Durations Are Conformant With a Power Law Based on System Size and Spatial Synchronization. Circ Arrhythm Electrophysiol. Published 28 June 2024. doi:10.
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