Coronary disease & ACS

STEMI, Revascularization, and Peak Troponin by Adverse Pregnancy Outcomes in Women With Myocardial Infarction

JACC AdvPublished Cohort study

Authors' conclusion

Among women with a first MI, a history of preterm preeclampsia or SGA infant were associated with STEMI and invasive revascularization.

Study context

Population
Women aged ≤65 years with first myocardial infarction (MI) in Sweden, 2007 to 2022
Participants
8,320 women
Exposure
History of adverse pregnancy outcomes vs no such history
Outcome
STEMI at presentation (also invasive revascularization, high troponin)
Methodological detailsnationwide (Sweden)
  • Nationwide (Sweden)

Main finding

As reported in the abstract

STEMI at presentation
Adjusted
Each group vs no such historyOdds ratio (95% CI)
Preterm preeclampsia
1.40(1.05–1.88)
SGA infant
1.30(1.13–1.50)
Women with STEMI overall
3,128 (38%)

Observational data: associations, not effects.

Further findings

In-hospital revascularization

Higher adjusted OR with preterm preeclampsia or SGA infant history

Troponin levels, stratified by infarct type

Did not differ by adverse pregnancy outcome history

Original publication

STEMI, Revascularization, and Peak Troponin by Adverse Pregnancy Outcomes in Women With Myocardial Infarction. JACC Adv. Published 5 July 2024. doi:10.1016/j.jacadv.2024.101088

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