Acute cardiac care & resuscitation
Sub30: Feasibility study of a pre-hospital extracorporeal membrane oxygenation (ECMO) in patients with refractory out-of-hospital cardiac arrest in London, United Kingdom
Authors' conclusion
Whilst our study did not meet primary outcome of achieving full ECPR flow within 30-minute of collapse, it demonstrated safe, timely and effective delivery of ECPR with comparable survival rates by pre-hospital teams in a large metropolitan city
Study context
- Population
- Patients with refractory OHCA in London, UK5 cannulated for ECPR
- Participants
- 43 patients
- Outcome
- Established on pre-hospital ECPR within 30 min of the call to the emergency services
Methodological detailsopen-label, 43 eligible patients identified over 27 recruitment days in 13 months; ECPR team despatched to 18
- Open-label
- 43 eligible patients identified over 27 recruitment days in 13 months; ECPR team despatched to 18
Main finding
As reported in the abstract
Established on pre-hospital ECPR within 30 min of call
Pre-hospital ECPR
0
events
Observational data: associations, not effects.
Further findings
Time from initial collapse to ECPR full flows
- Mean time from collapse to ECPR full flows, min (range 37-59)
- 47
- Cannulated patients, n = 5
Travel time to scene
- Median travel time to scene, min (range 3-20)
- 14
Treatment withdrawn
- Treatment withdrawn (of 5 patients)
- 3
Survival to hospital discharge
- Survived to hospital discharge (of 5 patients)
- 2
- Both CPC score 3; Modified Rankin Score (mRS) 4 and 5 respectively
Original publication
Sub30: Feasibility study of a pre-hospital extracorporeal membrane oxygenation (ECMO) in patients with refractory out-of-hospital cardiac arrest in London, United Kingdom. Resuscitation. Published 5 December 2024. doi:10. 1016/ j. resuscitation. 2024. 110455
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