Heart failure & cardiomyopathies

Change in Caregiver Health-Related Quality of Life From Before to Early After Surgery: SUSTAIN-IT Study

Circ Heart FailPublished Prospective cohort study

Authors' conclusion

Caregivers of older patients undergoing heart failure surgeries reported overall high HRQOL before and early post-surgery.

Study context

Population
Caregivers of older HF patients (60–80 years) undergoing heart transplantation (HT) or mechanical circulatory support (MCS) surgery
Participants
227 caregivers
Exposure
Caregivers of patients undergoing HT with pretransplant MCS vs HT without pretransplant MCS vs long-term MCS
  • HT MCSn = 54
  • HT non-MCSn = 76
  • Long-term MCSn = 97
Outcome
Caregiver HRQOL: EQ-5D-3 L visual analog scale (0 [worst]-100 [best])
Follow-up
Before and 3 and 6 months post-surgery
Methodological detailsmulticentre, 13 US sites
  • Multicentre
  • 13 US sites

Main finding

As reported in the abstract

EQ-5D visual analog scale (all caregivers)

Before surgery

84.8

SD 14.1

3 months

84.7

SD 13.0

6 months

83.9

SD 14.7

Observational data: associations, not effects.

Further findings

Factors associated with change in caregiver health-related quality of life (HRQOL)

β (95% CI)P value
Patient pulmonary hypertension presurgery−13.72 (−21.07 to −6.36)P < 0.001
Patient arrhythmia 3 to 6 months post-operatively−14.22 (−27.41 to −1.02)P = 0.035
Patient marital/partner status6.21 (1.34–11.08)P = 0.013
Presurgery coronary disease8.98 (4.07–13.89)P < 0.001

Original publication

Change in Caregiver Health-Related Quality of Life From Before to Early After Surgery: SUSTAIN-IT Study. Circ Heart Fail. Published 22 June 2023. doi:10.1161/circheartfailure.122.010038

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