Arrhythmias & electrophysiology
Systematic review of long QT syndrome identified during fetal life
Study context
- Population
- Fetuses with suspected long QT syndrome (LQTS) confirmed postnatally
- Participants
- 265 fetuses83 studies
- Outcome
- Prediction of death (adverse perinatal and postnatal outcomes)
Pooled result
As reported in the abstract
Antenatal predictors of death
Fetal QTc predicting death, ROC AUC
0.85
95% CI 0.66–1.00
Fetal heart rate predicting death, ROC AUC
0.51
95% CI 0.31–0.71
Heart rate z-score predicting death, ROC AUC
0.59
95% CI 0.37–0.80
Antenatal VT/TdP or functional 2:1 atrioventricular block (AVB) plus no family history of LQTS predicting death, ROC AUC
0.82
95% CI 0.76–0.88
Original publication
Systematic review of long QT syndrome identified during fetal life. Heart Rhythm. Published 22 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →