Heart failure & cardiomyopathies

Telehealth-Aided Outpatient Management of Acute Heart Failure in a Specialist Virtual Ward Compared with Standard Care

ESC Heart FailPublished Propensity score matched cohort study

Authors' conclusion

Telehealth-guided specialist HFVW management for ADHF may offer a safe and efficacious alternative to hospitalization in suitable patients.

Study context

Population
Patients with acute decompensated heart failure (HF) (ADHF), May 2022–October 2023 vs 2021 cohort
Participants
554 vs 404
Exposure
Telehealth-guided HF virtual ward vs standard care
  • HFVWn = 554
  • SCn = 404reference
Outcome
Re-hospitalizations and mortality
Follow-up
1, 3, 6 and 12 months

Main finding

As reported in the abstract

HFVW

Re-hospitalization 1 month
8.6%
Re-hospitalization 3 months
21%
Re-hospitalization 6 months
28%
Re-hospitalization 12 months
47%
Mortality 1 month
5%
Mortality 3 months
9.5%
Mortality 6 months
15%
Mortality 12 months
20%

SC

Re-hospitalization 1 month
21.5%
Re-hospitalization 3 months
30%
Re-hospitalization 6 months
41%
Re-hospitalization 12 months
57%
Mortality 1 month
13.7%
Mortality 3 months
15%
Mortality 6 months
21%
Mortality 12 months
26%

Re-hospitalization 1 month

HFVW8.6%
SC21.5%

Re-hospitalization 3 months

HFVW21%
SC30%

Re-hospitalization 6 months

HFVW28%
SC41%

Re-hospitalization 12 months

HFVW47%
SC57%

Mortality 1 month

HFVW5%
SC13.7%

Mortality 3 months

HFVW9.5%
SC15%

Mortality 6 months

HFVW15%
SC21%

Mortality 12 months

HFVW20%
SC26%
HFVW vs SCOdds ratio (95% CI)P value
Readmission, 1 month
0.3(0.2–0.5)
P < 0.0001
Readmission, 3 months
0.15(0.1–0.3)
P < 0.0001
Readmission, 6 months
0.35(0.2–0.6)
P = 0.0002
Readmission, 12 months
0.25(0.15–0.4)
P ≤ 0.001
Mortality, 1 month
0.26(0.14–0.48)
P < 0.0001
Mortality, 3 months
0.11(0.04–0.27)
P < 0.0001
Mortality, 6 months
0.35(0.2–0.61)
P = 0.0002
Mortality, 12 months
0.6(0.48–0.73)
P = 0.03

Observational data: associations, not effects.

Further findings

Predictor: higher GWTG-HF score · 1, 3, 6 and 12 months

Re-hospitalization OR 1/3/6/12 months
1.2 [1.1-1.3]; 1.5 [1.37; 1.64]; 1.3 [1.2-1.4]; 1.1 [1.05-1.2]
Mortality OR 1/3/6/12 months
1.21 [1.1-1.3]; 1.3 [1.2-1.4]; 1.2 [1.1-1.3]; 1.3 [1.1-1.7]

Predictor: higher clinical frailty score · 1, 3, 6 and 12 months

Re-hospitalization OR 1/3/6/12 months
1.9 [1.5-2.4]; 1.8 [1.3-2.4]; 1.4 [1.1-1.8]; 1.9 [1.2-3]
Mortality OR 1/3/6/12 months
2.1 [1.6-2.8]; 1.8 [1.2-2.6]; 2.34 [1.51-5.6]; 2.6 [1.6-7]

Predictor: increased daily step count on HFVW

Re-hospitalization OR 1 month
0.85[0.7-0.9]
Re-hospitalization OR 3 months
0.95 [0.93-0.98]
Mortality OR 1 month
0.85 [0.7-0.95]

Predictor: Charlson co-morbidity index, adverse outcomes · 12 months

OR
1.2 [1.1-1.4]
  • P = 0.03

Original publication

Telehealth-Aided Outpatient Management of Acute Heart Failure in a Specialist Virtual Ward Compared with Standard Care. ESC Heart Fail. Published 13 August 2024. doi:10.1002/ehf2.15003

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