Pulmonary vascular disease & thromboembolism

Temporal trends in the utilization of advanced therapies among patients with acute pulmonary embolism: insights from a national database

Eur Heart J Acute Cardiovasc CarePublished Retrospective cohort study

Study context

Population
Hospitalizations with acute pulmonary embolism (PE), Nationwide Readmissions Database (US), 2016–2020
Participants
920,770 hospitalizations
Outcome
Temporal trends in utilization of advanced PE therapies
Methodological detailsnational database
  • National database

Main finding

As reported in the abstract

Temporal trends in advanced PE therapy use, 2016-2020
  • Overall increase in use of advanced PE therapies, mainly systemic thrombolytics and catheter-directed therapies
  • Incremental increase in extracorporeal membrane oxygenation cannulation
  • Decline in inferior vena cava filter use
  • No change in surgical embolectomy use
  • Increase in advanced therapies at urban teaching but not urban non-teaching hospitals

Observational data: associations, not effects.

Further findings

Proportion diagnosed with high-risk PE

Increased over the study years

In-hospital mortality and 90-day unplanned readmission

No change in unadjusted or adjusted in-hospital mortality
90-day unplanned readmission rate declined

Original publication

Temporal trends in the utilization of advanced therapies among patients with acute pulmonary embolism: insights from a national database. Eur Heart J Acute Cardiovasc Care. Published 7 August 2023. doi:10.1093/ehjacc/zuad092

Composed by AI from the published abstract and checked against it. How Briefs are made →

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