Heart failure & cardiomyopathies
The Clinical Relevance of Quality of Life in Heart Failure Patients with Preserved Ejection Fraction
Authors' conclusion
EQ-5D-5L is useful tool for risk stratification in patients with HFpEF.
Study context
- Population
- Patients with HF with preserved ejection fraction (HFpEF) in the PURSUIT HFpEF study; EQ-5D-5L at discharge206 died
- Participants
- 864 patients
- Exposure
- EQ-5D-5L index tertiles
- Low EQ-5D-5Ln = 287
- Middle EQ-5D-5Ln = 293
- High EQ-5D-5Ln = 284reference
- Outcome
- All-cause mortality
- Follow-up
- Mean 2.0 ± 1.2 years
Main finding
As reported in the abstract
Mortality
Each group vs high EQ-5D-5LAdjusted hazard ratio (CI)P value
Low EQ-5D-5L
1.81(1.12–2.92)
P = 0.002Middle EQ-5D-5L
1.91(1.21–3.03)
P = 0.006Observational data: associations, not effects.
Further findings
EQ-5D-5L dimensions associated with all-cause mortality (multivariable-adjusted)
- Mobility
- P = 0.014
- Self-care
- P = 0.023
- Usual activities
- P = 0.008
Original publication
The Clinical Relevance of Quality of Life in Heart Failure Patients with Preserved Ejection Fraction. ESC Heart Fail. Published 12 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →