Ventricular septal defect characteristics influence presence of septal anatomical isthmuses in patients with repaired tetralogy of Fallot
Authors' conclusion
Ventricular septal defect characteristics aid in determining the presence of septal AIs potentially related to VT. In patients with doubly committed VSDs, septal VT substrates are unlikely.
Study context
- Population
- Patients with repaired tetralogy of Fallot who underwent electroanatomical mapping, 2005–2023, with surgical report of ventricular septal defect (VSD) details
- Participants
- 91 patients
- Exposure
- Septal anatomical isthmuses by VSD type
- Outlet perimembranous VSDn = 76
- Outlet muscular VSDn = 6
- Doubly committed juxta-arterial VSDn = 7
- Outcome
- Presence of septal anatomical isthmuses AI 3 (VSD–pulmonary annulus) and AI 4 (VSD–tricuspid annulus)
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Presence of AI 3 and AI 4
| Group | Anatomical isthmuses (AI) 3 | AI 4 | AI 4, muscular postero-inferior rim | AI 4, fibrous postero-inferior rim |
|---|---|---|---|---|
| Outlet perimembranous VSD | 97% | 0 | ||
| Outlet muscular VSD | 83% | 33% | ||
| Doubly committed juxta-arterial VSD | 0 | 50% | 0 |
Anatomical isthmuses (AI) 3
Outlet perimembranous VSD97%
Outlet muscular VSD83%
Doubly committed juxta-arterial VSD0
AI 4
Outlet perimembranous VSD0
Outlet muscular VSD33%
Doubly committed juxta-arterial VSDNot reported in the abstract
AI 4, muscular postero-inferior rim
Outlet perimembranous VSDNot reported in the abstract
Outlet muscular VSDNot reported in the abstract
Doubly committed juxta-arterial VSD50%
AI 4, fibrous postero-inferior rim
Outlet perimembranous VSDNot reported in the abstract
Outlet muscular VSDNot reported in the abstract
Doubly committed juxta-arterial VSD0
Observational data: associations, not effects.
Original publication
Ventricular septal defect characteristics influence presence of septal anatomical isthmuses in patients with repaired tetralogy of Fallot. Europace. Published 16 December 2024. doi:10.
Summarised from the published abstract; every number is checked against it