Trends in Risk Factor Prevalence and Incidence of Acute Myocardial Infarction in Young Adults
Authors' conclusion
Young adults with AMI have a different and increasing burden of both traditional and nontraditional RFs compared to older adults. These findings could help guide strategies for primary prevention of AMI.
Study context
- Population
- Young and older adults hospitalized with incident AMI, National Inpatient Sample, 2011 to 2021
- Participants
- 4,431,901 incident AMI hospitalizations
- Comparison
- Young adults compared to older adults
- Young adultsn = 974,521
Methodological detailsstratified by age, subgroup analysis by sex and race/ethnicity
- Stratified by age
- Subgroup analysis by sex and race/ethnicity
Primary result
As reported in the abstract
Most prevalent RFs in young adults overall
Hypertension
64.8%
Tobacco use
57.8%
Further findings
Traditional risk factors (RFs) (5), young vs older adults
- Tobacco smoking and obesity significantly higher in young adults compared to older adults
Nontraditional RFs (12), young vs older adults
- Lowest income quartile, family history of ischemic heart disease, and psychiatric disorders significantly higher in young adults
RF prevalence within young adults by sex and race/ethnicity (subgroup)
- Women and non-Whites had a higher prevalence of both traditional and nontraditional RFs
Trends in RF prevalence in young adults · 2011 to 2021
- Prevalence of most traditional and nontraditional RFs in young adults increased significantly
- P for trend < 0.050 for all
Original publication
Trends in Risk Factor Prevalence and Incidence of Acute Myocardial Infarction in Young Adults. JACC Adv. Published 20 August 2025. doi:10.
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