Valvular & structural heart disease
Tricuspid edge-to-edge repair for tricuspid valve prolapse and flail leaflet: feasibility in comparison to patients with secondary tricuspid regurgitation
Authors' conclusion
T-TEER confers equally safe and effective reduction of TR in patients with primary and secondary TR.
Study context
- Population
- Symptomatic patients with TR at high operative risk assigned to transcatheter tricuspid edge-to-edge repair (T-TEER) by the heart team13% primary, 87% secondary TR
- Participants
- 339 patients
- Exposure
- T-TEER in primary TR vs secondary TR
- Outcome
- Procedural results (TR reduction; TR vena contracta width)
Methodological detailsconsecutive recruitment, two European centres, propensity score matching
- Consecutive recruitment
- Two European centres
- Propensity score matching
Main finding
As reported in the abstract
TR vena contracta width
| Group | Value | Pre-interventional |
|---|---|---|
| Primary TR | 4 (SD 3) mm | 13 ± 4 mm |
| Secondary TR | 5 (SD 5) mm | 14 ± 5 mm |
Value
Primary TR4 (SD 3) mm
Secondary TR5 (SD 5) mm
Pre-interventional
Primary TR13 ± 4 mm
Secondary TR14 ± 5 mm
- Primary TR vs Secondary TR: P = 0.10 — post-interventional
- Primary TR vs Secondary TR: P = 0.19 — pre-interventional
Observational data: associations, not effects.
Further findings
Baseline cardiac characteristics
RV basal diameter Primary TR 45 mm · Secondary TR 49 mm
RV fractional area change Primary TR 45% · Secondary TR 41%
Right atrium Primary TR 28 cm² · Secondary TR 34 cm²
Left atrium Primary TR 52 mL/m² · Secondary TR 67 mL/m²
LVEF
- Baseline cardiac characteristics: RV diameter P = 0.004
- Baseline cardiac characteristics: FAC P = 0.001
- Baseline cardiac characteristics: RA P = 0.021
- Baseline cardiac characteristics: LA P = 0.038
- Baseline cardiac characteristics: LVEF P = 0.005
Safety
- Complications similar between both groups
Original publication
Tricuspid edge-to-edge repair for tricuspid valve prolapse and flail leaflet: feasibility in comparison to patients with secondary tricuspid regurgitation. Eur Heart J Cardiovasc Imaging. Published 20 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →