Valvular & structural heart disease
TRIVALVE Score: A Risk Score for Mortality/Hospitalization Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention
Authors' conclusion
The present study proposes a dedicated risk score for patients undergoing TTVI, providing an additional and simple tool for heart teams to select the best therapy for patients affected by severe TR.
Study context
- Population
- Patients with severe tricuspid regurgitation (TR) undergoing transcatheter tricuspid valve intervention (TTVI) (TRIVALVE registry)
- Participants
- 483 patients
- Outcome
- Mortality or rehospitalization
- Follow-up
- 12 months
Methodological detailsregistry-based, multisite registry, multivariable logistic regression, bootstrapping with 1,000 resamples
- Registry-based
- Multisite registry
- Multivariable logistic regression
- Bootstrapping with 1,000 resamples
Performance
As reported in the abstract
Risk score performance for 12-month mortality or rehospitalization
- Overall 12-month mortality or rehospitalization rate
- 19% (n = 94)
- Score range
- 0 to 4.5
- Score parameters (adjusted for age and gender): AF at baseline; GFR <30 mL/min; elevated gamma-glutamyl transferase/bilirubin; signs of right HF; LVEF <50%
- 5
- Bias-corrected AUC
- 68% (95% CI: 62%-75%)
- Cutoff 2.5 sensitivity
- 65.4%
- Cutoff 2.5 specificity
- 60.5%
Original publication
TRIVALVE Score: A Risk Score for Mortality/Hospitalization Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention. JACC Cardiovasc Interv. Published 23 September 2024. doi:10. 1016/ j. jcin. 2024. 08. 009
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