Valvular & structural heart disease

TRIVALVE Score: A Risk Score for Mortality/Hospitalization Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention

JACC Cardiovasc IntervPublished Risk score derivation and internal validation study

Authors' conclusion

The present study proposes a dedicated risk score for patients undergoing TTVI, providing an additional and simple tool for heart teams to select the best therapy for patients affected by severe TR.

Study context

Population
Patients with severe tricuspid regurgitation (TR) undergoing transcatheter tricuspid valve intervention (TTVI) (TRIVALVE registry)
Participants
483 patients
Outcome
Mortality or rehospitalization
Follow-up
12 months
Methodological detailsregistry-based, multisite registry, multivariable logistic regression, bootstrapping with 1,000 resamples
  • Registry-based
  • Multisite registry
  • Multivariable logistic regression
  • Bootstrapping with 1,000 resamples

Performance

As reported in the abstract

Risk score performance for 12-month mortality or rehospitalization
Overall 12-month mortality or rehospitalization rate
19% (n = 94)
Score range
0 to 4.5
Score parameters (adjusted for age and gender): AF at baseline; GFR <30 mL/min; elevated gamma-glutamyl transferase/bilirubin; signs of right HF; LVEF <50%
5
Bias-corrected AUC
68% (95% CI: 62%-75%)
Cutoff 2.5 sensitivity
65.4%
Cutoff 2.5 specificity
60.5%

Original publication

TRIVALVE Score: A Risk Score for Mortality/Hospitalization Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention. JACC Cardiovasc Interv. Published 23 September 2024. doi:10.1016/j.jcin.2024.08.009

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