Pulmonary vascular disease & thromboembolism

Advanced Echocardiographic Assessment Predicts 1-Year Mortality in Critically Ill Patients With Pulmonary Arterial Hypertension

JACC AdvPublished Retrospective cohort study

Authors' conclusion

In critically ill PAH patients, echocardiographic markers were independently associated with mortality.

Study context

Population
Critically ill patients with pulmonary arterial hypertension (PAH) admitted to the ICU, January 2010 to December 202077 with adequate echocardiograms
Participants
102 patients
Outcome
In-hospital and 1-year mortality

Main finding

As reported in the abstract

Random survival forest (RSF) model (tricuspid annular plane systolic excursion (TAPSE), LV diastolic filling parameters, LV end-diastolic volume, fractional area change/PASP) time-varying AUC

0.84

Observational data: associations, not effects.

Original publication

Advanced Echocardiographic Assessment Predicts 1-Year Mortality in Critically Ill Patients With Pulmonary Arterial Hypertension. JACC Adv. Published 27 August 2025. doi:10.1016/j.jacadv.2025.102080

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