Pulmonary vascular disease & thromboembolism
Right ventricular strain related to pulmonary artery pressure predicts clinical outcome in patients with pulmonary arterial hypertension
Main finding · Death or heart/lung transplantationResult — go to the resultHazard ratio 8.3 95% CI 3.2–21.6Authors' conclusion
RVFW LS/sPAP ratio significantly predicts all-cause mortality and heart-lung transplantation, and was superior to other well-established parameters, in patients with pre-capillary PAH.
Study context
- Population
- Patients with pre-capillary pulmonary arterial hypertension (PAH)45 females
- Participants
- 65 patients
- Exposure
- RVFW longitudinal strain (LS)/sPAP ratio vs other echocardiographic parameters for prognosis
- Outcome
- Death or heart/lung transplantation
Main finding
As reported in the abstract
Hazard ratio
8.3
95% CI 3.2–21.6
P < 0.001
RVFW LS/sPAP ratiovs other echocardiographic parameters for prognosis
HR 8.3 (95% CI 3.2–21.6); P < 0.001
- RVFW LS/sPAP (cut-off 0.19) sensitivity
- 92%
- RVFW LS/sPAP (cut-off 0.19) specificity
- 82.5%
Observational data: associations, not effects.
Further findings
Characteristics of patients reaching the endpoint
- Worse NYHA functional capacity, reduced right ventricle (RV) function and higher sPAP in patients reaching the endpoint
- LV function similar in both groups
Original publication
Right ventricular strain related to pulmonary artery pressure predicts clinical outcome in patients with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. Published 19 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →