Heart failure & cardiomyopathies
Assessing Potassium Levels in Critically Ill Patients with Heart Failure: Application of a Group-Based Trajectory Model
Authors' conclusion
Critically ill patients with HF have blood potassium trajectories. And the trajectories are associated with all-cause mortality for hyperkalaemia and normal blood potassium-level patients.
Study context
- Population
- Critically ill patients with heart failure (HF) admitted to the intensive care unit (ICU) (mean age 71.81 ± 13.12 years, 54.90% males)
- Participants
- 4,053 patients
- Exposure
- Potassium trajectory groups within initial potassium categories
- Hypokalaemian = 336
- Normal blood potassium-leveln = 3,322reference
- Hyperkalaemian = 395
- Outcome
- All-cause mortality by potassium trajectory
- Follow-up
- 28 day and 365 day
Methodological detailsgroup-based trajectory modelling, Potassium measured 9 times after ICU admission
- Group-based trajectory modelling
- Potassium measured 9 times after ICU admission
Main finding
As reported in the abstract
All-cause mortality
Hazard ratio (95% CI)P value
Hyperkalaemia: high-level declinevs Hyperkalaemia: low-level stable28 day; adjusted
2.917(1.555–5.473)
P < 0.05Hyperkalaemia: high-level declinevs Hyperkalaemia: low-level stable365 day; adjusted
2.854(1.820–4.475)
P < 0.05Normal: medium-level stablevs Normal: low-level stable28 day; adjusted
0.776(0.657–0.918)
P < 0.05Normal: medium-level stablevs Normal: low-level stable365 day; adjusted
0.827(0.733–0.934)
P < 0.05Observational data: associations, not effects.
Original publication
Assessing Potassium Levels in Critically Ill Patients with Heart Failure: Application of a Group-Based Trajectory Model. ESC Heart Fail. Published 24 September 2022. doi:10.
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