Arrhythmias & electrophysiology
Autothreshold algorithm feasibility and safety in left bundle branch pacing
Authors' conclusion
The autothreshold algorithm is feasible in LBBP, with a favourable trend towards bipolar pacing. Automatic thresholds are similar to manual in patients with LBBP, and they remain stable during follow-up.
Study context
- Population
- Consecutive patients with indication for cardiac pacing
- Participants
- 75 patients
- Exposure
- Left bundle branch pacing (LBBP) vs conventional pacing
- LBBPn = 50
- Conventional pacingn = 25reference
- Outcome
- Behaviour of the autothreshold algorithm (feasibility of activation; automatic vs manual thresholds)
- Follow-up
- Acute, subacute (1-7 days) and chronic (1-3 months) phases
Methodological detailsnon-randomized, single-centre
- Non-randomized
- Single-centre
Main finding
As reported in the abstract
LBBP: no statistically significant differences between manual and automatic thresholds; both stable during follow-up (mean increase)
0.50 V
Observational data: associations, not effects.
Further findings
Causes of failure of algorithm activation
Insufficient safety margins
Atrial tachyarrhythmias
Electrical noise LBBP 6.9%
Original publication
Autothreshold algorithm feasibility and safety in left bundle branch pacing. Europace. Published 3 December 2023. doi:10.
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