Heart failure & cardiomyopathies
Biatrial arrhythmogenic substrate in patients with hypertrophic obstructive cardiomyopathy
Authors' conclusion
In patients with HOCM, conduction disorders, LVA, and FP are equally present in both atria, supporting the hypothesis of a primary atrial myopathy.
Study context
- Population
- Hypertrophic obstructive cardiomyopathy (HOCM) patients (age 50 ± 12 years) mapped during sinus rhythm
- Participants
- 15 patients
- Comparison
- Right atrium (RA) vs left atrium (LA)
- Outcome
- Prevalence of conduction delay, conduction block, potential fractionation and low-voltage areas, RA vs LA
Methodological detailsintraoperative epicardial mapping
- Intraoperative epicardial mapping
Main finding
As reported in the abstract
FP with low-voltage components
| Outcome | RA | LA | P value |
|---|---|---|---|
| Conduction delay | 2.9% [1.9%-3.6%] | 2.6% [2.1%-6.4%] | P = 0.541 |
| Conduction block | 1.7% [0.9%-3.1%] | 1.5% [0.5%-2.8%] | P = 0.600 |
| LVA | 4.7% [1.6%-7.7%] | 2.9% [2.1%-7.1%] | P = 0.793 |
| SP voltage P75 | 7.3 mV | 10.9 mV | |
| FP voltage P75 | 2.0 mV | 3.7 mV |
Original publication
Biatrial arrhythmogenic substrate in patients with hypertrophic obstructive cardiomyopathy. Heart Rhythm. Published 20 January 2024. doi:10.
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