Valvular & structural heart disease

Clinical utility and prognostic value of right atrial function in severe tricuspid regurgitation: one more piece of the puzzle

Eur Heart J Cardiovasc ImagingPublished Prospective cohort study

Authors' conclusion

RA function by 2D-STE independently predicts mortality and HF hospitalizations in patients with ≥ severe TR.

Study context

Population
Consecutive patients with at least severe tricuspid regurgitation (TR) evaluated in a Heart Valve Clinic
Participants
140 / 20 / 20
Exposure
≥ severe TR vs controls vs permanent isolated atrial fibrillation (AF)
  • ≥ severe TRn = 140
  • Controln = 20reference
  • AFn = 20
Outcome
Combined endpoint of HF hospital admission or all-cause mortality
Follow-up
Median 2.2 years
Methodological detailsconsecutive patients, Heart Valve Clinic
  • Consecutive patients
  • Heart Valve Clinic

Main finding

As reported in the abstract

RA reservoir strain (RASr) and outcomes · median follow-up 2.2 years (IQR: 12-41 months)

RASr cut-off with best accuracy to predict outcomes

<9.4%

Observational data: associations, not effects.

Further findings

RASr by group

≥ severe TR showed lower RASr vs controls and AF group
P < 0.001

RASr by TR aetiology

Atrial TR showed lower RASr vs other aetiologies of TR
P < 0.001

Original publication

Clinical utility and prognostic value of right atrial function in severe tricuspid regurgitation: one more piece of the puzzle. Eur Heart J Cardiovasc Imaging. Published 19 April 2023. doi:10.1093/ehjci/jead052

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