Arrhythmias & electrophysiology

Feasibility study: Characterizing acute lesion dimensions in patients with and without devices using noncontrast (native T1-weighted) magnetic resonance imaging after ventricular tachycardia/premature ventricular complex radiofrequency ablation

Heart RhythmPublished Feasibility study

Authors' conclusion

Native T1w MRI can effectively characterize lesion dimensions in patients with and without implantable cardioverter-defibrillators within 7 days after ablation.

Study context

Population
Patients with and without ICDs within 7 days of VT/PVC radiofrequency ablation (RFA)
Participants
10 patients
Comparison
Native T1-weighted (T1w) magnetic resonance imaging (MRI) vs LGE MRI for RFA lesion dimensions
Outcome
Feasibility of wideband native T1w MRI in characterizing lesion dimensions
Follow-up
Within 7 days of RFA

Main finding

As reported in the abstract

Mean microvascular obstruction (MVO) surface area greater than mean native T1w lesion surface area
P = .0108
Mean MVO volume greater than mean native T1w lesion volume
P = .0376
Correlation of average surface area, MVO vs native T1w
r = 0.71, P = .0237
Correlation of average volume, MVO vs native T1w
r = 0.70, P = .0265

Further findings

Native T1w maximum lesion depth vs ablation parameters

Correlation with average ablation duration
r = 0.73, P = .02
Correlation with average impedance drop
r = 0.68, P = .04

Original publication

Feasibility study: Characterizing acute lesion dimensions in patients with and without devices using noncontrast (native T1-weighted) magnetic resonance imaging after ventricular tachycardia/premature ventricular complex radiofrequency ablation. Heart Rhythm. Published 20 June 2025. doi:10.1016/j.hrthm.2025.06.024

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