Valvular & structural heart disease

Feasibility of redo-TAVI in the self-expanding ACURATE neo2 valve: a computed tomography study

EuroInterventionPublished Computed tomography simulation study

Authors' conclusion

The feasibility of redo-TAVI with an S3 in an ACn2 depends on the implant depth of the S3 and the geometry of the surrounding aorta.

Study context

Population
Patients after TAVI with the self-expanding ACURATE neo2 (ACn2) valve, simulated redo-TAVI with balloon-expandable SAPIEN 3 (S3)post-ACn2 TAVI CT scans
Participants
153 patients
Comparison
Low vs high S3 implant position for redo-TAVI within ACn2
Outcome
Risk of coronary flow compromise and coronary inaccessibility (neoskirt height and valve-to-aorta distances)

Main finding

As reported in the abstract

Risk of coronary flow compromise

Further findings

Unrestricted coronary access (predicted)

Coronary access unrestricted with low S3 implantation
52%
Coronary access unrestricted with high S3 implantation
13%

Independent predictors of high risk of coronary flow compromise

Female sex, small aortic annular dimension and STJ-to-aortic annulus mean diameter ratio <1.15 were independent predictors

Original publication

Feasibility of redo-TAVI in the self-expanding ACURATE neo2 valve: a computed tomography study. EuroIntervention. Published 18 November 2024. doi:10.4244/eij-d-24-00367

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