Arrhythmias & electrophysiology
Identification of causative organisms using enrichment cultures for cardiac implantable electronic device infections
Authors' conclusion
Utilization of enrichment cultures could highlight a disparity in pathogen distribution compared with previous reports. Cutibacterium acnes played a particularly significant role as the causative pathogen in the late onset of CIED infections.
Study context
- Population
- Patients with cardiac implantable electrical device (CIED) infectionspatients with CIED infections analyzed
- Participants
- 117 patients
- Comparison
- Late vs early onset CIED infections; enrichment cultures vs conventional blood agar cultures
- Early groupn = 45
- Late groupn = 72
- Outcome
- Causative microorganisms identified using enrichment culture
Main finding
As reported in the abstract
Cases with causative microorganisms identified
97%
Staphylococcus species
63%
Cutibacterium acnes
18%
Further findings
Cutibacterium acnes frequency · significantly higher in late infections
P = 0.02
Staphylococcus aureus frequency · lower in late infections
P = 0.04
Characteristics of early infections
- Early infections: more pocket infections, fewer male patients, lower left ventricular ejection fraction, higher brain natriuretic peptide level, lower renal function
Detection rate of causative organisms, enrichment vs conventional blood agar cultures
- Significantly higher detection rate with enrichment cultures, regardless of bacterial species
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →