Acute cardiac care & resuscitation

Impact of Mitral Valve Transcatheter Edge-To-Edge Repair on Haemodynamic Parameters in Cardiogenic Shock

ESC Heart FailPublished retrospective study

Authors' conclusion

Our study demonstrates that TEER leads to favourable haemodynamic changes in patients with CS. We observed a significant reduction in left atrial pressure, V-wave, and an elevation in cardiac index. Importantly, we did not observe any deterioration in left ventricular function following the procedure. This supports the concept of haemodynamic stabilization with TEER in patients with CS and high-grade mitral regurgitation.

Study context

Population
Patients undergoing transcatheter edge-to-edge repair (TEER) for mitral valve regurgitation in the setting of cardiogenic shock (CS)patients who underwent TEER in the context of CS
Participants
25 patients
Exposure
Haemodynamic and echocardiographic parameters before and after TEER
Outcome
Procedural success (mitral regurgitation reduction)

Main finding

As reported in the abstract

  • All patients were successfully treated with at least of one grade reduction in mitral regurgitation

Observational data: associations, not effects.

Further findings

Left atrial mean pressure · following the procedure · decreased

P < 0.01

V-wave · following the procedure · decreased

P < 0.01

Stroke volume index · increased

P < 0.01

Cardiac index · increased

P < 0.01

Ejection fraction · after the procedure

We did not observe any worsening of the ejection fraction after the procedure

In-hospital death · during their hospital stay

Patients who died during their hospital stay
Ten patients (40%)

Original publication

Impact of Mitral Valve Transcatheter Edge-To-Edge Repair on Haemodynamic Parameters in Cardiogenic Shock. ESC Heart Fail. Published 14 April 2025. doi:10.1002/ehf2.15306

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