Heart failure & cardiomyopathies
Inferior vena CAVA and lung ultraSound-guided therapy in acute heart failure: A randomized pilot study (CAVAL US-AHF study)
Authors' conclusion
IVC and lung ultrasound-guided therapy in AHF patients significantly reduced subclinical congestion at discharge.
Study context
- Population
- Patients hospitalised with acute HF
- Participants
- 60 patients
- Comparison
- Inferior vena cava (IVC) and lung ultrasound-guided therapy vs standard care
- CAVAL USn = 30
- Controln = 30reference
- Primary endpoint
- Subclinical congestion: >5 B-lines and/or increased IVC diameter and collapsibility
- Follow-up
- Discharge
Methodological detailsinvestigator-initiated, single-centre, single-blind, pilot
- Investigator-initiated
- Single-centre
- Single-blind
- Pilot
Primary result
As reported in the abstract
P < 0.001
Secondary outcomes
HF readmission, unplanned visit for worsening HF or death (exploratory) · 90 days · log rank
P = 0.038
| Outcome | CAVAL US | Control | P value |
|---|---|---|---|
| NT-proBNP reduction · dischargeNot significant | 48% (IQR 27–67) | 37% (IQR −3–59) | P = 0.09 |
Original publication
Inferior vena CAVA and lung ultraSound-guided therapy in acute heart failure: A randomized pilot study (CAVAL US-AHF study). Am Heart J. Published 31 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →