Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava
Authors' conclusion
A 3D modeling workflow with CFD simulation for SV patients with iIVC may avoid HVF maldistribution and development of AVMs after Fontan completion.
Study context
- Population
- Single ventricle patients with interrupted IVC and azygos continuation undergoing Fontan completion or revision (3 revision candidates with existing arteriovenous malformations (AVMs))
- Participants
- 4 patients
- Outcome
- Hepatic venous flow distribution to the lungs after Fontan surgery
Methodological detailscomputational fluid dynamics modelling, virtual surgery
- Computational fluid dynamics modelling
- Virtual surgery
Main finding
As reported in the abstract
Computational fluid dynamics (CFD)-predicted hepatic venous flow (HVF) to one lung with existing or proposed Fontan completion (all patients)
100%
Average HVF distribution to right/left pulmonary arteries with CFD-guided alternative approaches
37%/63% ± 10.4%
Observational data: associations, not effects.
Further findings
Validation: predicted pre-operative vs postoperative MRI-measured total right/left pulmonary flow
- Predicted pre-operative right/left pulmonary flow
- 51%/49% ± 5.4%
- Postoperative MRI-measured right/left pulmonary flow
- 49%/51% ± 8.5%
Original publication
Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava. JACC Adv. Published 13 June 2024. doi:10.
Summarised from the published abstract; every number is checked against it