Heart failure & cardiomyopathies
Optimizing ventricular scar characterization in late-gadolinium enhancement cardiac MRI: Impact of thresholding techniques in magnitude and phase-sensitive reconstructed images
Authors' conclusion
This study demonstrates significant differences in myocardial scar metrics based on reconstruction and thresholding techniques.
Study context
- Population
- Patients with ischaemic cardiomyopathy with an ICD undergoing late gadolinium enhancement (LGE) CMR32 primary-prevention ICD
- Participants
- 80 patients
- Exposure
- Phase-sensitive inversion recovery (PSIR) vs magnitude (MAG) reconstruction, FWHM vs n-SD thresholding for LGE scar quantification
- Outcome
- Scar metrics by reconstruction and thresholding
Main finding
As reported in the abstract
PSIR showed significantly larger scar metrics than MAG using FWHM and n-SD, including border zone
16.43 ± 8.15 g vs 21.42 ± 10.72 g
P<.001
Observational data: associations, not effects.
Further findings
Primary vs secondary prevention ICD
- MAG: larger border zone and conduction corridor (CC) length in primary prevention; similar trends for PSIR
Original publication
Optimizing ventricular scar characterization in late-gadolinium enhancement cardiac MRI: Impact of thresholding techniques in magnitude and phase-sensitive reconstructed images. Heart Rhythm. Published 13 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →