Heart failure & cardiomyopathies
Predicting Heart Failure Symptoms from the Apnoea–Hypopnoea Index Determined by Full-Night Polysomnography
Authors' conclusion
In patients with SDB who are at risk of heart failure, severe SDB is associated with a high risk of all-cause mortality and the development of heart failure.
Study context
- Population
- Patients at risk of HF (Stage A or B) undergoing full-night polysomnography, Nippon Medical School Chiba Hokusoh Hospital, December 2010–June 2017
- Participants
- 230 patients
- Exposure
- Apnoea-hypopnoea index (AHI) ≥ 41.6 vs AHI < 41.6 events/hour
- Hn = 115
- Ln = 115reference
- Outcome
- Composite of all-cause mortality plus hospitalization due to HF
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
P = 0.027
Observational data: associations, not effects.
Further findings
Factors associated with the composite endpoint (multivariate analyses)
| HR (95% CI) | P value | ||
|---|---|---|---|
| AHI | 1.02 (1.00–1.04) | P = 0.024 | |
| Haemoglobin | 0.71 (0.54–0.94) | P = 0.017 | |
| Left atrial dimension | 1.10 (1.03–1.18) | P = 0.006 | |
| 0.512Hazard ratio (log scale) |
- Minimum SpO2 during polysomnography (PSG) (<80%) not associated with the composite endpoint
Original publication
Predicting Heart Failure Symptoms from the Apnoea–Hypopnoea Index Determined by Full-Night Polysomnography. ESC Heart Fail. Published 15 May 2024. doi:10.
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