Cardio-oncology & otherCohort study
Pregnancy outcomes in women with a history of myocarditis
- retrospective study
Authors' conclusion
Most women with prior myocarditis do not develop adverse cardiac events. However, echocardiographic surveillance during pregnancy may still be helpful to identify decreases in LV systolic function.
Study context
- Population
- Pregnant women with prior history of myocarditis/perimyocarditis followed in a CardioObstetrics Program (1998–2025)women, 36 pregnancies
- Participants
- 27 women
Main finding
As reported in the abstract
- Maternal death
- Heart failure
- Sustained arrhythmia
No adverse maternal cardiac events, pregnancies
97% (35/36)
Developed heart failure (moderately reduced left ventricular (LV) systolic function during myocarditis, recovered prior to pregnancy)
One patient
Observational data: associations, not effects.
Further findings
Maternal or fetal deaths
- There were no maternal or fetal deaths
Premature delivery (31-36 weeks)
- Pregnancies with premature delivery
- Thirteen percent
Baseline characteristics
- Mean age
- 33 ± 4.9 years
- Median interval between myocarditis and pregnancy
- 5.0 years
- Moderate/severe LV systolic dysfunction at myocarditis presentation, cases
- 50%
- Full recovery of LV systolic function prior to pregnancy, among pregnancies with significant LV dysfunction at myocarditis presentation
- 83%,15/18
Reduction in LV systolic function in pregnancy (mild/normal to moderate/severely reduced)
- Patients with reduction in LV systolic function
- Two
Original publication
Summarised from the published abstract; every number is checked against it