Arrhythmias & electrophysiology
Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry
Authors' conclusion
This is the largest multicentre study demonstrating the feasibility of EACNA with encouraging intermediate-term outcomes in selected patients with VAVB.
Study context
- Population
- Patients with symptomatic paroxysmal or persistent vagally induced AV block (VAVB)
- Participants
- 130 patients
- Outcome
- Syncope and daytime second- or advanced-degree AVB on serial prolonged ECG monitoring
- Follow-up
- During
Methodological detailsinternational, 20 centres
- International
- 20 centres
Main finding
As reported in the abstract
Syncope or daytime second- or advanced-degree AVB on serial prolonged ECG monitoring · median follow-up 300 days (150, 496)
Primary outcome in cases with acute procedural success
17 of 125
14%
Recurrence of AVB
9
New syncope
8
Observational data: associations, not effects.
Further findings
Acute procedural success (acute reversal of AVB and complete abolition of atropine response)
- Acute procedural success
- 96.2%
Factors associated with primary outcome
- Operator experience and use of extracardiac vagal stimulation similar with and without primary outcome
- History of AF, hypertension and CAD associated with higher primary outcome occurrence
Pacemaker placement during follow-up
- Patients with primary outcome requiring pacemaker placement
- 4
Original publication
Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry. Europace. Published 2 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →