Acute cardiac care & resuscitation

Prognostic factors for out-of-hospital cardiac arrest patients with prolonged low-flow time undergoing extracorporeal cardiopulmonary resuscitation

Eur Heart J Acute Cardiovasc CarePublished Secondary analysis of the SAVE-J II registry study

Authors' conclusion

Approximately 10% of OHCA patients who underwent ECPR with LFT ≥ 60 min had favourable neurological outcomes.

Study context

Population
Non-hypothermic adult out-of-hospital cardiac arrest (OHCA) patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) with low-flow time ≥ 60 min, Japan, 2013–2018
Participants
708 patients
Primary endpoint
Favourable neurological outcome (cerebral performance categories 1-2)
Follow-up
Hospital discharge
Methodological detailsretrospective, multicentre, 36 institutions in Japan
  • Retrospective
  • Multicentre
  • 36 institutions in Japan

Primary result

As reported in the abstract

Favourable neurological outcome

Favourable neurological outcome at discharge

71

10.0%

Original publication

Prognostic factors for out-of-hospital cardiac arrest patients with prolonged low-flow time undergoing extracorporeal cardiopulmonary resuscitation. Eur Heart J Acute Cardiovasc Care. Published 13 May 2025. doi:10.1093/ehjacc/zuaf072

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