Prognostic Value of Microvascular Resistance Reserve After Percutaneous Coronary Intervention in Patients With Myocardial Infarction
Pooled resultResult — go to the resultHazard ratio 4.16 95% CI 2.31–7.50Authors' conclusion
MRR measured directly after primary percutaneous coronary intervention was an independent predictor of the composite of all-cause mortality or hospitalization for heart failure during long-term follow-up.
Study context
- Population
- Patients with STEMI with index of microcirculatory resistance (IMR) and microvascular resistance reserve (MRR) measured directly after primary PCIpooled cohort n = 1,265
- Participants
- 446 patients
- Comparison
- Low MRR vs high MRR after primary PCI
- Outcome
- Composite of:
- All-cause mortality
- Hospitalization for HF
- Follow-up
- Median 3.1 years (Q1-Q3: 1.5-6.1 years)
Methodological detailssubgroup analysis
- Subgroup analysis
Pooled result
As reported in the abstract
Hazard ratio
4.16
95% CI 2.31–7.50
P < 0.001
By group
Low MRRvs High MRR
HR 4.16 (95% CI 2.31–7.50); P < 0.001
Further pooled results
Independent predictors of the primary endpoint
- Both IMR and MRR were independent predictors of all-cause mortality or HF hospitalization
Original publication
Prognostic Value of Microvascular Resistance Reserve After Percutaneous Coronary Intervention in Patients With Myocardial Infarction. J Am Coll Cardiol. Published 3 May 2024. doi:10. 1016/ j. jacc. 2024. 02. 052
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