Arrhythmias & electrophysiology
Radiofrequency-aided venous ethanol vs optimized radiofrequency for primary and repeat ablation of left ventricular summit arrhythmias: A propensity score-matched comparison
Authors' conclusion
When venous mapping supports intramural origin, RF-aided venous ethanol ablation is an effective strategy for the treatment of LVSA also when compared to ORF ablation.
Study context
- Population
- Patients undergoing primary or repeat ablation of left ventricular summit arrhythmiasmatched from 43 coronary venous ethanol ablation (CVEA) ± radiofrequency (RF) and 93 optimized RF (ORF)
- Participants
- 41 vs 41
- Exposure
- CVEA ± RF vs optimized RF
- CVEA ± RFn = 41
- ORFn = 41reference
- Outcome
- Recurrence
- Follow-up
- Median 24 (12-58) months
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
P = 0.002
Observational data: associations, not effects.
Further findings
Acute procedural success
P = 0.077
Ventricular premature beat burden decrease
P = 0.041
VT burden decrease (patients with VT)
| Outcome | P value |
|---|---|
| Pace-match (venous vs conventional mapping) | P < 0.0001 |
| Earliest presystolic signalVenous mapping vs Conventional mapping | P < 0.0001 |
- VT burden decrease (patients with VT): CVEA ± RF P < .0001; ORF reduction not significant
- Pace-match (venous vs conventional mapping): Venous mapping mean 97.1 (SD 1.7) %
- Pace-match (venous vs conventional mapping): Conventional mapping mean 94.7 (SD 3) %
- Earliest presystolic signal: Venous mapping −41 (SD 11) ms
- Earliest presystolic signal: Conventional mapping −28 (SD 10) ms
Safety
| Outcome | CVEA ± RF | ORF |
|---|---|---|
| Complications | ||
| Pericarditis | — not stated in the abstract | 1 |
| Tamponade | — not stated in the abstract | 1 |
| Atrioventricular block | — not stated in the abstract | 1 |
| Vascular access complication | 1 | — not stated in the abstract |
— not stated in the abstract
- Complications — Deaths
- 0
Original publication
Radiofrequency-aided venous ethanol vs optimized radiofrequency for primary and repeat ablation of left ventricular summit arrhythmias: A propensity score-matched comparison. Heart Rhythm. Published 30 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →