Aortic & peripheral vascular disease

Rehospitalisations, repeated aortic surgery, and death in initial survivors of surgery for Stanford type A aortic dissection and the significance of age - a nationwide registry-based cohort study

Eur Heart J Qual Care Clin OutcomesPublished Retrospective cohort study

An erratum to this article was published (Eur Heart J Qual Care Clin Outcomes, 21 Jun 2023 ↗)

Main finding · DeathResult — go to the resultHazard ratio 2.44 95% CI 1.37–4.34

Authors' conclusion

Rehospitalisations in the first year after discharge were common in all age groups, but survival was high. Repeated aortic surgery was significantly more common among younger than older patients.

Study context

Population
Survivors of hospitalization and surgery on the ascending aorta and/or aortic arch for Stanford type A aortic dissection, Danish nationwide registries (2006–2018)
Participants
606 survivors
Exposure
Age groups: <60 vs 60-69 vs >69 years
  • Group In = 36reference
  • Group IIn = 194
  • Group IIIn = 176
Outcome
Rehospitalization, repeated aortic surgery and death
Methodological detailsnationwide registry-based
  • Nationwide registry-based

Main finding

Death · After 10 years

Hazard ratio

2.44

95% CI 1.37–4.34

By group

Group IIIvs group I
HR 2.44 (95% CI 1.37–4.34)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeGroup IGroup IIGroup IIIHR (95% CI)
Repeated aortic surgery · After 10 yearsGroup IIIvs group IMultivariable Cox11.5%8.5%1.6%0.17 (0.04–0.78)

Death · First year

Repeated aortic surgery — Overall repeated aortic surgery
8.0%
Death — Overall death
5.9%
  • Repeated aortic surgery: P = 0.04 across groups
  • Death: P = 0.04 across groups

Rehospitalization and repeated aortic surgery · First year

Re-hospitalized, no significant difference across age groups
62.5%
Repeated aortic surgery, no significant difference across age groups
1.4%
  • P = 0.68 and P = 0.39, respectively

Original publication

Rehospitalisations, repeated aortic surgery, and death in initial survivors of surgery for Stanford type A aortic dissection and the significance of age - a nationwide registry-based cohort study. Eur Heart J Qual Care Clin Outcomes. Published 28 September 2022. doi:10.1093/ehjqcco/qcac061

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