Congenital heart disease

Serial cardiopulmonary exercise testing in young patients after one-and-half ventricle repair and Fontan procedure: a comparative study

Eur Heart J Qual Care Clin OutcomesPublished Retrospective cohort study

Authors' conclusion

These findings suggest that the 1.5VR may provide superior long-term functional outcomes than the Fontan procedure in patients with borderline HRV.

Study context

Population
Young patients with borderline hypoplastic RV after 1.5VR or univentricular heart after Fontan; Cardiopulmonary exercise tests (CPETs) September 2002–March 2024age at baseline 8.6 ± 2.6 years
Participants
43 patients
Exposure
1.5VR vs Fontan
  • 1.5VRn = 10
  • FSLVn = 21reference
  • FSRVn = 12reference
Outcome
Cardiorespiratory fitness and efficiency on serial CPET
Follow-up
10-year follow-up
Methodological detailsserial CPETs, ≥10 years follow-up
  • Serial CPETs
  • ≥10 years follow-up

Main finding

As reported in the abstract

Cardiorespiratory fitness and efficiency
  • 1.5VR had higher cardiorespiratory fitness and efficiency vs FSLV and FSRV

Observational data: associations, not effects.

Further findings

Cardiorespiratory fitness and efficiency at first CPET · baseline

No differences among the three groups

Original publication

Serial cardiopulmonary exercise testing in young patients after one-and-half ventricle repair and Fontan procedure: a comparative study. Eur Heart J Qual Care Clin Outcomes. Published 23 May 2024. doi:10.1093/ehjqcco/qcae041

Summarised from the published abstract; every number is checked against it

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