Valvular & structural heart disease
The prevalence, aetiologies, and clinical consequences of tricuspid regurgitation associated with severe degenerative mitral regurgitation
Authors' conclusion
In patients with severe DMR, TR presents with different aetiologies, clinical features, and echocardiographic phenotypes that require a comprehensive assessment at the time of DMR surgery to ensure the best management for these patients.
Study context
- Population
- Patients with severe degenerative mitral regurgitation (DMR)
- Participants
- 884 patients
- Exposure
- Tricuspid valve prolapse (TVP) vs atrial functional TR (AFTR) vs ventricular functional TR (VFTR) vs Mixed
- TVPn = 487
- AFTRn = 172
- VFTRn = 42
- Mixedn = 183
- Outcome
- Prevalence, aetiologies and clinical consequences of TR
Main finding
As reported in the abstract
TR aetiology
- ≥ moderate tricuspid regurgitation (TR)
- 31%
Observational data: associations, not effects.
Further findings
Independent predictors of TV intervention
| OR (95% CI) | P value | ||
|---|---|---|---|
| TA dilatation | 3.68 (2.05–6.62) | P < 0.001 | |
| >mild TR | 9.30 (5.10–16.95) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
| Outcome | AFTR |
|---|---|
| MV surgery and simultaneous TV intervention | |
| TV intervention | 32% |
- Mitral valve (MV) surgery and simultaneous TV intervention — MV surgery
- 785 (88%)
- MV surgery and simultaneous TV intervention — Simultaneous TV intervention
- 132 (15%)
Original publication
The prevalence, aetiologies, and clinical consequences of tricuspid regurgitation associated with severe degenerative mitral regurgitation. Eur Heart J Cardiovasc Imaging. Published 27 August 2024. doi:10.
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