Arrhythmias & electrophysiology

Vector field heterogeneity as a novel omnipolar mapping metric for functional substrate characterization in scar-related ventricular tachycardias

Heart RhythmPublished Mechanistic study

Authors' conclusion

VFH mapping identified a significant increase in electrical heterogeneity at IS compared with bystanders with highest heterogeneity at the entrance. Yet, absolute differences were small, and substantial overlap among sites was recorded, precluding its use as a stand-alone mapping approach.

Study context

Population
Patients with scar-related ventricular tachycardia (VT) undergoing substrate mapping with a 16-pole grid catheter9 endocardial, 7 epicardial maps
Participants
16 patients
Comparison
Isthmus sites (IS) vs LVA vs NVA
Outcome
Vector field heterogeneity (VFH; 0 = perfect planar wave to 1 = maximal disorganization)

Main finding

As reported in the abstract

VFH

IS

0.57

± 0.26

LVA

0.52

± 0.34

NVA

0.16

± 0.24

IS vs LVA: P < 0.001 · NVA vs IS and LVA: P < 0.001

Further findings

OutcomeEntryExit
VFH within the isthmus0.61 ± 0.240.44 ± 0.27

Vector field heterogeneity (VFH) within the isthmus

Highest heterogeneity at entry, lowest at exit sites

Original publication

Vector field heterogeneity as a novel omnipolar mapping metric for functional substrate characterization in scar-related ventricular tachycardias. Heart Rhythm. Published 7 November 2024. doi:10.1016/j.hrthm.2024.10.066

Summarised from the published abstract; every number is checked against it

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