Arrhythmias & electrophysiology
Ventricular Parasystole in Cardiomyopathy Patients: A Link Between His-Purkinje System Damage and Ventricular Fibrillation
Authors' conclusion
Ventricular parasystole was strongly associated with new conduction system abnormalities and VF in patients who have cardiomyopathy with ICDs, suggesting a potential link between VF and His-Purkinje damage in this patient population.
Study context
- Population
- Cardiomyopathy patients with implantable cardioverter-defibrillators (ICDs) undergoing ICD interrogation, June 2019–August 2020
- Participants
- 374 patients
- Exposure
- Ventricular parasystole vs no parasystole
- Parasystolen = 33
- Outcome
- Prevalence of ventricular parasystole and its association with ventricular fibrillation (VF), ventricular tachycardia (VT) and new conduction system abnormalities
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
VF
P < 0.01
VT
P = 0.12
- Prevalence of ventricular parasystole
- 9%
Observational data: associations, not effects.
Further findings
Progressive intraventricular conduction delay (≥5 years of intrinsic QRS ECGs) · 11 of 18 vs 12 of 83
P < 0.01
New right bundle branch block (≥5 years of intrinsic QRS ECGs) · 4 of 18 vs 1 of 83
P < 0.01
Original publication
Ventricular Parasystole in Cardiomyopathy Patients: A Link Between His-Purkinje System Damage and Ventricular Fibrillation. JACC Clin Electrophysiol. Published 22 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →